Abnova

GAK Polyclonal Antibody, MaxPab™

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GAK Antibody (H00002580-D01P) in WB

Western Blot analysis of GAK expression in transfected 293T cell line (H00002580-T01) by GAK MaxPab polyclonal antibody.

Lane 1: GAK transfected lysate(44.00 KDa).
Lane 2: Non-transfected lysate.

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产品信息

H00002580-D01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

GAK (AAH08668.1, 1 a.a. approximately 416 a.a) full-length human protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: MSLLQSALDF LAGPGSLGGA SGRDQSDFVG QTVELGELRL LLASPAPPLS VQSTPRGGPP AAADPFGPLL PSSGNNSQPC SNPDLFGEFL NSDSVTVPPS FPSAHSSPPP SCSADFLHLG DLPGEPSKMT ASSSNPDLLG GWAAWTETAA SAVAPTPATE GPLFSPGGQP APCGSQASWT KSQNPDPFAD LGDLSSGLQG SPAGFPPGGF IPKTATTPKG SSSWQTSRPP AQGASWPPQA KPPPKACTQP RPNYASNFSV IGAREERGVR APSFAQKPKV SENDFEDLLS NQGFSSRSDK KGPKTIAEMR KQDLAKDTDP LKLKLLDWIE GKERNIRALL STLHTVLWDG ESRWTPVGMA DLVAPEQVKK HYRRAVLAVH PDKAAGQPYE QHAKMIFMEL NDAWSEFENQ GSRPLF

靶标信息

GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。