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Positive Samples: HT-29, BT-474, MCF-7, SW480, Mouse kidney; Cellular Location: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein
Immunogen sequence: VQYSKEESRM ERNMKNKNKM LDLMLEAVNN IKDAMPKMQI GAPVRQNIDA GERPCLQGYY TAAELKPVLD RPPQDSNAPG ASGKAFKTTN LSVEEQKEKE RGEAKHCFNA FASDRISL
GALNT3 encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein is highly homologous to other family members, however the enzymes have different substrate specificities.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GalNAc transferase 3; GalNAc-T3; Polypeptide GalNAc transferase 3; polypeptide GalNAc-transferase T3; Polypeptide N-acetylgalactosaminyltransferase 3; pp-GaNTase 3; ppGaNTase-T3; Protein-UDP acetylgalactosaminyltransferase 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
基因别名: GalNAc-T3; GALNT3; HFTC; HHS
UniProt ID: (Human) Q14435, (Mouse) P70419
Entrez Gene ID: (Human) 2591, (Rat) 366061, (Mouse) 14425
分子生物学功能:
glycosyltransferase