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Invitrogen
GARS Polyclonal Antibody
高级验证
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
产品信息
PA5-96322
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 60-370 of human GARS (NP_0020382)
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808124
产品详细信息
Immunogen sequence: AEEVLAPLRL AVRQQGDLVR KLKEDKAPQV DVDKAVAELK ARKRVLEAKE LALQPKDDIV DRAKMEDTLK RRFFYDQAFA IYGGVSGLYD FGPVGCALKN NIIQTWRQHF IQEEQILEID CTMLTPEPVL KTSGHVDKFA DFMVKDVKNG ECFRADHLLK AHLQKLMSDK KCSVEKKSEM ESVLAQLDNY GQQELADLFV NYNVKSPITG NDLSPPVSFN LMFKTFIGPG GNMPGYLRPE TAQGIFLNFK RLLEFNQGKL PFAAAQIGNS FRNEISPRSG LIRVREFTMA EIEHFVDPSE KDHPKFQNVA D; Positive Samples: Jurkat, 293T, U-87MG, Raji, M21, HT-29, Mouse brain, Mouse spinal cord; Cellular Location: Cell projection, Cytoplasm, Mitochondrion, axon
靶标信息
GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 6.1.1.14; AP-4-A synthetase; Ap4A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; Diadenosine tetraphosphate synthetase; EC 2.1.2.29; GARTF; glycine tRNA ligase; Glycine--tRNA ligase; Glycyl-tRNA synthetase; Glycyl-tRNA synthetase 1; GlyRS; MGC47764; PAIS; PGFT; PRGS; storage granule protein 23
基因别名: CMT2D; DSMAV; GARS; GARS1; Gena201; GENA202; GlyRS; HMN5; Nmf249; RGD1559871; Sgrp23; SMAD1
UniProt ID: (Human) P41250, (Rat) Q5I0G4, (Mouse) Q9CZD3
Entrez Gene ID: (Human) 2617, (Rat) 297113, (Mouse) 353172
