Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 1
GATA5 Antibody (BS-1779R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded rat lung; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with GATA5 Polyclonal Antibody, Unconjugated (bs-1779R) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB s... View More
产品信息
BS-1779R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human GATA-5, amino acids 161-260.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
GATA binding factor 5 is a transcription regulator involved in embryonic development. In addition, the protein encoded by this gene contains two GATA-type zinc fingers and is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha). This interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. GATA-5 may be involved in the establishment of cardiac smooth muscle cell diversity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: GATA binding factor-5; GATA-binding factor 5; GATA-binding protein 5; Transcription factor GATA-5; Transcription factor GATA-5 (GATA binding factor-5)
基因别名: bB379O24.1; GATA5; GATAS
UniProt ID: (Human) Q9BWX5, (Mouse) P97489
Entrez Gene ID: (Human) 140628, (Mouse) 14464, (Rat) 499951
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
zinc ion binding
transcription regulatory region DNA binding
DNA binding
protein binding
sequence-specific DNA binding
metal ion binding
DNA-binding transcription factor
transcription from RNA polymerase II promoter
heart development
blood coagulation
organ morphogenesis
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
cell development
anatomical structure formation involved in morphogenesis
intestinal epithelial cell differentiation
cellular response to BMP stimulus
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
