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GBA3 Antibody (MA5-24342) in ICC/IF
Immunocytochemistry analysis of GBA3 in immersion fixed HeLa human cervical epithelial carcinoma cell line. Samples were incubated in GBA3 monoclonal antibody (Product # MA5-24342) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red, upper panel) and counterstained with DAPI (blue, lower panel). Specific staining was localized to cytoplasm.
产品信息
MA5-24342
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
728702
抗原
Sf 21-derived recombinant human Cytosolic beta-Glucosidase/GBA3 Thr13-Leu469
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2605478
产品详细信息
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1; Cytosolic galactosylceramidase; Cytosolic GCase; Cytosolic glucosylceramidase; Cytosolic glycosylceramidase; Glucosidase beta acid 3; glucosidase, beta, acid 3 (cytosolic); Glucosylceramidase beta 3; Klotho-related protein; KLrP
基因别名: CBG; CBGL1; GBA3; GLUC; KLRP
UniProt ID: (Human) Q9H227
Entrez Gene ID: (Human) 57733
