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产品信息
H00002637-M09
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4B11
抗原
GBX2 (NP_001476, 141 a.a. approximately 230 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: AEALQADAED GKGFLAKEGS LLAFSAAETV QASLVGAVRG QGKDESKVED DPKGKEESFS LESDVDYSSD DNLTGQAAHK EEDPGHALEE *
靶标信息
Altered expression of GBX2, part of the homeobox-containing human family of DNA-binding transcription factors, is associated with therapy failure and death in patients with multiple types of cancer.
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生物信息学
蛋白别名: Gastrulation and brain-specific homeobox protein 2; Homeobox protein GBX-2; Stimulated by retinoic acid gene 7 protein
基因别名: D130058E05Rik; Gbx-2; GBX2; MMoxA; Stra7
UniProt ID: (Human) P52951, (Mouse) P48031
Entrez Gene ID: (Human) 2637, (Mouse) 14472
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
sequence-specific DNA binding
homeodomain transcription factor
patterning of blood vessels
neural crest cell migration
transcription from RNA polymerase II promoter
nervous system development
axon guidance
cerebellum development
midbrain-hindbrain boundary morphogenesis
rhombomere 2 development
thalamus development
forebrain neuron development
cerebellar granule cell precursor proliferation
inner ear morphogenesis
positive regulation of transcription from RNA polymerase II promoter
autonomic nervous system development
transcription, DNA-templated
regulation of transcription, DNA-templated
cell proliferation
hindbrain development
midbrain-hindbrain boundary development
tube morphogenesis
