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产品信息
PA5-29438
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 277 of Human GCM1
偶联物
形式
Liquid
浓度
0.84 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546914
产品详细信息
Recommended positive controls: HepG2, HepG2 nucleus.
Predicted reactivity: Mouse (84%), Rat (84%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chorion-specific transcription factor GCMa; GCM motif protein 1; Glial cells missing homolog 1; hGCMa
基因别名: GCM1; GCMA; hGCMa
UniProt ID: (Human) Q9NP62
Entrez Gene ID: (Human) 8521
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
zinc ion binding
histone deacetylase binding
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
anatomical structure morphogenesis
gliogenesis
positive regulation of transcription from RNA polymerase II promoter
calcium ion homeostasis
astrocyte fate commitment
positive regulation of syncytium formation by plasma membrane fusion
branching involved in labyrinthine layer morphogenesis
cell differentiation involved in embryonic placenta development
