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GCNF Antibody (MA5-17140) in ICC/IF
Immunofluorescence analysis of HepG2 cells using NR6A1 monoclonal antibody (Product # MA5-17140) (Green). Blue: DRAQ5 fluorescent DNA dye.
产品信息
MA5-17140
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
4G8
抗原
Purified recombinant fragment of human NR6A1 (amino acids: 65-118) expressed in E. Coli.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2538611
产品详细信息
MA5-17140 targets NR6A1 in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples.
The MA5-17140 immunogen is purified recombinant fragment of human NR6A1 (amino acids: 65-118) expressed in E. Coli.
MA5-17140 detects NR6A1 which has a predicted molecular weight of approximately 54.3kDa.
靶标信息
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GCNF; Germ cell nuclear factor; germ cell nuclear factor variant 1; h hRTR; Nuclear receptor subfamily 6 group A member 1; nuclear receptor subfamily 6, group A, member 1; retinoic acid receptor-related testis-associated receptor; Retinoid receptor-related testis-specific receptor; RTR
基因别名: CT150; GCNF; GCNF1; hGCNF; hRTR; NR61; NR6A1; RTR
UniProt ID: (Human) Q8NHQ0
Entrez Gene ID: (Human) 2649
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
steroid hormone receptor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
zinc ion binding
protein homodimerization activity
sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
gamete generation
spermatogenesis
cell proliferation
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
