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In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human GFR alpha -3 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GDNF family receptor alpha-2; GDNF re; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; GDNFR-beta; GFR-alpha 2; GFR-alpha-2; glial cell line derived neurotrophic factor receptor, beta; HpV18gp1; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored
基因别名: GDNFRB; GFRA2; NRTNR-ALPHA; NTNRA; RETL2; TRNR2
UniProt ID: (Human) O00451, (Mouse) O08842
Entrez Gene ID: (Human) 2675, (Mouse) 14586