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GGPS1 Antibody (PA5-12168) in IHC (P)
Immunohistochemistry analysis of GGPS1 in formalin-fixed and paraffin-embedded human breast carcinoma tissue. Samples were incubated with GGPS1 polyclonal antibody (Product # PA5-12168) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
产品信息
PA5-12168
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human GGPS1
偶联物
形式
Liquid
纯化类型
Ammonium sulfate precipitation
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2110992
靶标信息
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; geranylgeranyl pyrophosphate synthetase; Geranyltranstransferase; GGPP synthase; GGPP synthetase; GGPPSase
基因别名: 1810026C22Rik; 9530089B04Rik; AI843169; C79210; GGPPS; GGPPS1; GGPS1
UniProt ID: (Human) O95749, (Mouse) Q9WTN0
Entrez Gene ID: (Human) 9453, (Mouse) 14593
dimethylallyltranstransferase activity
farnesyltranstransferase activity
geranyltranstransferase activity
protein binding
metal ion binding
prenyltransferase activity
protein geranylgeranyltransferase activity
protein prenyltransferase activity
4-hydroxybenzoate octaprenyltransferase activity
protoheme IX farnesyltransferase activity
transferase activity
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity
cadaverine aminopropyltransferase activity
agmatine aminopropyltransferase activity
1,4-dihydroxy-2-naphthoate octaprenyltransferase activity
trans-pentaprenyltranstransferase activity
ATP dimethylallyltransferase activity
ADP dimethylallyltransferase activity
