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GGT1 Antibody (PA5-120579) in IHC (P)
Immunohistochemistry analysis of GGT1 in paraffin-embedded human breast cancer using. Samples were incubated with GGT1 Polyclonal antibody (Product # PA5-120579) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-120579
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 370-569 of human GGT1 (NP_0382652?)
偶联物
形式
Liquid
浓度
0.64 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914151
产品详细信息
Positive test controls include: Jurkat, Mouse kidney. The target is usually found in the following locations: Cell membrane, Single-pass type II membrane protein.
Immunogen sequence: KPEFYTPDDG GTAHLSVVAE DGSAVSATST INLYFGSKVR SPVSGILFNN EMDDFSSPSI TNEFGVPPSP ANFIQPGKQP LSSMCPTIMV GQDGQVRMVV GAAGGTQITT ATALAIIYNL WFGYDVKRAV EEPRLHNQLL PNVTTVERNI DQAVTAALET RHHHTQIAST FIAVVQAIVR TAGGWAAASD SRKGGEPAGY
靶标信息
Glutamyltransferase (gGT) from human kidney is a membrane-bound enzyme that transfers the gamma-glutamly moiety of gamma-glutamyl compounds such as glutathione to an acceptor, which may be an amino acid or a di- or tripeptide or water. The principal functions of gGT may be hydrolysis and metabolism of glutathione. Various human gGT isoforms have been found. The molecular mass of gGT for normal kidney is 90kDa and gGT can be used as a renal cell marker.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD224; gamma glutamyl-transferase 1; gamma-glutamyl transpeptidase; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1; GGT 1; glutathione hydrolase 1; Glutathione hydrolase 1 proenzyme; Leukotriene-C4 hydrolase; testicular tissue protein Li 73
基因别名: CD224; D22S672; D22S732; dwg; GGLUT; GGT; GGT 1; GGT-1; GGT1; Ggtp; GTG
UniProt ID: (Human) P19440, (Mouse) Q60928, (Rat) P07314
Entrez Gene ID: (Human) 2678, (Mouse) 14598, (Rat) 116568
regulation of immune system process
cellular amino acid metabolic process
glutamate metabolic process
leukotriene metabolic process
glutathione metabolic process
glutathione biosynthetic process
glutathione catabolic process
xenobiotic metabolic process
spermatogenesis
cysteine biosynthetic process
leukotriene biosynthetic process
zymogen activation
regulation of inflammatory response
proteolysis
aging
peptide modification
response to estradiol
response to lipopolysaccharide
cellular response to oxidative stress
response to tumor necrosis factor
