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Transcription coactivator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (PubMed:19392710). Appears to function synergistically with GRF1 as a transcriptional coactivator. Acts together with GRF5 for the development of appropriate leaf size and shape through the promotion and/or maintenance of cell proliferation activity in leaf primordia. Plays a role in adaxial/abaxial patterning and growth in leaf morphogenesis. GIFs are involved in the positive regulation of cell proliferation of lateral organs in a functionally redundant manner. Together with GATA18/HAN, mediates cotyledon identity by preventing ectopic root formation through the repression of PLT1 expression (PubMed:22669825).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AN3; AtGIF1; GRF1-interacting factor 1; Protein ANGUSTIFOLIA 3; putative transcription co-activator; Transcription coactivator GIF1
基因别名: AN3; ANGUSTIFOLIA 3; ARABIDOPSIS GRF1-INTERACTING FACTOR 1; AT5G28640; ATGIF1; F4I4.20; F4I4_20; GIF; GIF1; GRF1-INTERACTING FACTOR; GRF1-INTERACTING FACTOR 1
UniProt ID: (Arabidopsis) Q8L8A5
Entrez Gene ID: (Arabidopsis) 832968
分子生物学功能:
transcription cofactor