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GIP Antibody (PA5-120977) in IHC (P)
Immunohistochemistry analysis of GIP in paraffin-embedded mouse intestine. Samples were incubated with GIP Polyclonal antibody (Product # PA5-120977) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-120977
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 22-153 of human GIP (NP_004114.1).
偶联物
形式
Liquid
浓度
0.58 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914549
产品详细信息
Positive test controls include: Mouse small intestine. The target is usually found in the following locations: Secreted.
Immunogen sequence: EKKEGHFSAL PSLPVGSHAK VSSPQPRGPR YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI TQREARALEL ASQANRKEEE AVEPQSSPAK NPSDEDLLRD LLIQELLACL LDQTNLCRLR SR
靶标信息
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gastric inhibitory polypeptide; GIP; Glucose-dependent insulinotropic peptide; Glucose-dependent insulinotropic polypeptide; Incretin hormone; Rabbit Anti GIP
基因别名: GIP; Gludins; RATGLUDINS
UniProt ID: (Human) P09681, (Mouse) P48756, (Rat) Q06145
Entrez Gene ID: (Human) 2695, (Mouse) 14607, (Rat) 25040
signal transduction
female pregnancy
memory
adult locomotory behavior
response to glucose
response to selenium ion
response to acidic pH
positive regulation of glucose transport
response to organic cyclic compound
sensory perception of pain
endocrine pancreas development
positive regulation of insulin secretion
response to lipid
exploration behavior
response to drug
response to starvation
response to amino acid
response to peptide hormone
positive regulation of cAMP-mediated signaling
response to axon injury
regulation of insulin secretion
digestive system development
long-term synaptic potentiation
positive regulation of glucagon secretion
triglyceride homeostasis
positive regulation of synaptic transmission
response to carbohydrate
response to nutrient levels
