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GLAST Antibody (PA5-90649) in WB
Western blot analysis of GLAST in extracts of various cell lines. Samples were incubated with GLAST Polyclonal antibody (Product # PA5-90649) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-90649
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 453-542 of human EAAT1/EAAT1/SLC1A3 (NP_0041633)
偶联物
形式
Liquid
浓度
0.87 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806161
产品详细信息
Immunogen sequence: IVLTSVGLPT DDITLIIAVD WFLDRLRTTT NVLGDSLGAG IVEHLSRHEL KNRDVEMGNS VIEENEMKKP YQLIAQDNET EKPIDSETKM; Positive Samples: 293T, U-251MG, HeLa, H460, C6, Rat lung; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EAAT-1; Excitatory amino acid transporter 1; FLJ25094; GLAST; GLAST-1; Glial glutamate transporter; Glial high affinity glutamate transporter; GluT-1; glutamate transporter; glutamate/aspartate transporter; High-affinity neuronal glutamate transporter; Sodium-dependent glutamate/aspartate transporter 1; solute carrier family 1 (glial high affinity glutamate transporter), member 3; Solute carrier family 1 member 3; solute carrier family 1, member 3
基因别名: AI504299; B430115D02Rik; EA6; EAAT1; GLAST; GLAST-1; GLAST1; GLU-T; GluT-1; Gmt1; MGluT1; SLC1A3
UniProt ID: (Human) P43003, (Rat) P24942, (Mouse) P56564
Entrez Gene ID: (Human) 6507, (Rat) 29483, (Mouse) 20512
neurotransmitter uptake
positive regulation of defense response to virus by host
amino acid transmembrane transport
glutamate biosynthetic process
ion transport
chemical synaptic transmission
sensory perception of sound
response to light stimulus
gamma-aminobutyric acid biosynthetic process
response to wounding
glutamate secretion
cranial nerve development
auditory behavior
response to drug
malate-aspartate shuttle
response to antibiotic
cell morphogenesis involved in neuron differentiation
positive regulation of synaptic transmission
neuromuscular process controlling balance
L-glutamate import
D-aspartate import
L-glutamate transmembrane transport
mitophagy in response to mitochondrial depolarization
xenophagy
glutamate metabolic process
neurotransmitter transport
response to inorganic substance
L-glutamate transport
sodium ion transmembrane transport
transport
dicarboxylic acid transport
response to amino acid
