Invitrogen

GLI2 Recombinant Superclonal Antibody (9HCLC)

图: 1 / 1

GLI2 Antibody (711045) in WB

Western blot analysis was performed on Nuclear enriched extracts (30 µg lysate) of MDA-MB-231 (Lane 1), MDA-MB-231 treated with TGF-β1 (Serum starved and treated with 5 ng/mL for 48hr) (Lane 2), MCF-7 (Lane 3), MCF-7 treated with TGF-β1 (Serum starved and treated with 5 ng/mL for 48hr) (Lane 4), A549 (Lane 5), A549 treated with TGF-β1 (Serum starved and treated with 5 ng/mL for 48hr) (Lane 6) and tissue extracts of mouse pancreas (Lane 7), Rat Pancreas (Lane 8) and Mouse Kidney (Lane 9). The blots were probed with Anti-Gli-2 Recombinant Ra... View More

Product Image Gallery

产品信息

711045

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Superclonal

类型

Antibody

克隆号

9HCLC

抗原

Protein corresponding to Human GLI2 (aa 1-332)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.2

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2633108

产品详细信息

This antibody is predicted to react with Monkey, Pig, Bovine and Rabbit

Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

靶标信息

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: GLI family zinc finger protein 2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; oncogene GLI2; Tax helper protein; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; Zinc finger protein GLI2

查看更多收起

基因别名: AW546128; CJS; GLI2; HPE9; PHS2; THP; THP1; THP2

查看更多收起

UniProt ID: (Human) Q15591, (Mouse) Q0VGT2

查看更多收起

Entrez Gene ID: (Human) 2736, (Rat) 304729, (Mouse) 14633

查看更多收起

功能