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Sequence of this protein is as follows: MAAGAAEAAV AAVEEVGSAG QFEELLRLKA KSLLVVHFWA PWAPQCAQMN EVMAELAKEL PQVSFVKLEA EGVPEVSEKY EISSVPTFLF FKNSQKIDRL DGAHAPELTK KVQRHASSGS FLPSANEHLK EDLNLRLKKL THAAPCMLFM KGTPQEPRCG FSKQMVEILH KHNIQFSSFD IFSDEEVRQG LKAYSSWPTY PQLYVSGELI GGLDIIKELE ASEELDTICP KAPKLEERLK VLTNKASVML FMKGNKQEAK CGFSKQILEI LNSTGVEYET FDILEDEEVR QGLKAYSNWP TYPQLYVKGE LVGGLDIVKE LKENGELLPI LRGEN
This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bA500G10.4; FLJ11864; glutaredoxin 4; Glutaredoxin-3; PICOT; PKC interacting cousin of thioredoxin; PKC-interacting cousin of thioredoxin; PKC-theta-interacting protein; PKCq-interacting protein; testicular tissue protein Li 75; thioredoxin-like 2; Thioredoxin-like protein 2
基因别名: GLRX3; GLRX4; GRX3; GRX4; HUSSY-22; PICOT; TXNL2; TXNL3
UniProt ID: (Human) Q9P1B1, (Mouse) Q9CQM9
Entrez Gene ID: (Human) 10539, (Mouse) 30926