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GLUT4 Antibody (PA5-142587) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of GLUT4 in NIH3T3 cells using GLUT4 Polyclonal Antibody (Product # PA5-142587). Cells were fixed with paraformaldehyde, permeabilized with 0.15% Triton, and incubated with the primary antibody for 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing membrane and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
产品信息
PA5-142587
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-NLEGPARKSLKRLT.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2933233
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
靶标信息
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glucose transporter glut4; Glucose transporter type 4, insulin-responsive; GLUT-4; GT2; MGC93607; Solute carrier family 2, facilitated glucose transporter member 4
基因别名: Glut-4; Glut4; Slc2a4
UniProt ID: (Mouse) P14142
Entrez Gene ID: (Mouse) 20528
transport
carbohydrate transport
amylopectin biosynthetic process
glucose transport
proton transport
cellular response to insulin stimulus
hexose transmembrane transport
glucose homeostasis
glucose import
brown fat cell differentiation
transmembrane transport
cellular response to hypoxia
cellular response to osmotic stress
cation transmembrane transport
