Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
BS-13452R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human GM2A/SAP3, amino acids 131-193.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Cerebroside sulfate activator protein; Ganglioside GM2 activator; GM2 ganglioside activator protein; GM2-AP; SAP-3; shingolipid activator protein 3; Sphingolipid activator protein 3
基因别名: GM2-AP; GM2A; SAP-3
UniProt ID: (Human) P17900
Entrez Gene ID: (Human) 2760, (Rat) 282838
glycosphingolipid metabolic process
ganglioside catabolic process
lipid transport
learning or memory
oligosaccharide catabolic process
lipid storage
neuromuscular process controlling balance
positive regulation of hydrolase activity
ganglioside metabolic process
positive regulation of catalytic activity
neurological system process
membrane fusion
