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Recommended positive controls: A431, HeLaS3.
Predicted reactivity: Mouse (100%), Rat (99%), Zebrafish (96%), Xenopus laevis (97%), Pig (100%), Chicken (97%), Bovine (100%), Guinea pig (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Guanine nucleotide-binding proteins (G proteins) form a large family of signal-transducing molecules. They are found as heterotrimers made up of alpha, beta, and gamma subunits. Members of the G protein family have been characterized most extensively on the basis of the alpha subunit, which binds guanine nucleotide, is capable of hydrolyzing GTP, and interacts with specific receptor and effector molecules. The G protein family includes Gs and Gi, the stimulatory and inhibitory GTP-binding regulators of adenylate cyclase; Go, a protein abundant in brain; and transducin-1 and transducin-2, proteins involved in phototransduction in retinal rods and cones, respectively.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adenylate cyclase-inhibiting G alpha protein; Gi1 protein alpha subunit; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; Guanine nucleotide-binding protein G(i) subunit alpha-1
基因别名: Gi; GNAI1
UniProt ID: (Human) P63096
Entrez Gene ID: (Human) 2770
分子生物学功能:
heterotrimeric G-protein