Proteintech

GNAT1 Polyclonal Antibody

GNAT1 Antibody in Immunocytochemistry (ICC/IF)

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GNAT1 Antibody (55167-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 55167-1-AP (GNAT1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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产品信息

55167-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看5篇已发表文章 5篇已发表文章

免疫组化 (IHC)

查看2篇已发表文章 2篇已发表文章

免疫细胞化学 (ICC/IF)

1:50-1:500

查看1篇已发表文章 1篇已发表文章

其他PubMed (Misc)

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不适用 (N/A)

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产品规格

种属反应

Human, Mouse

已发表种属

Zebrafish

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.23 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

This antibody is specific to GNAT1.

靶标信息

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phosphodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice.

The FEBS journal

Li X,Jiang Z,Su Y,Wang K,Jiang X,Sun K,Yang Y,Zhou Y,Zhu X,Zhang L

Fri Sep 01 00:00:00 EDT 2023

Deletion of Emc1 in photoreceptor cells causes retinal degeneration in mice.

The FEBS journal

Li X,Jiang Z,Su Y,Wang K,Jiang X,Sun K,Yang Y,Zhou Y,Zhu X,Zhang L

Fri Sep 01 00:00:00 EDT 2023

Knockout of DLIC1 leads to retinal cone degeneration via disturbing Rab8 transport in zebrafish.

Biochimica et biophysica acta. Molecular basis of disease

Zhang J,Jing M,Li P,Sun L,Pi X,Jiang N,Zhu KK,Li H,Li J,Wang M,Zhang J,Liu M,Mu H,Hu Y,Cui X

Sat Apr 01 00:00:00 EDT 2023

Frmpd1 Facilitates Trafficking of G-Protein Transducin and Modulates Synaptic Function in Rod Photoreceptors of Mammalian Retina.

eNeuro

Campla CK,Bocchero U,Strickland R,Nellissery J,Advani J,Ignatova I,Srivastava D,Aponte AM,Wang Y,Gumerson J,Martemyanov K,Artemyev NO,Pahlberg J,Swaroop A

Fri Oct 21 00:00:00 EDT 2022

Robust visual cortex evoked potentials (VEP) in Gnat1 and Gnat2 knockout mice.

Frontiers in cellular neuroscience

Flood MD,Veloz HLB,Hattar S,Carvalho-de-Souza JL

Wed Jan 11 00:00:00 EST 2023

Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease.

iScience

Zhang J,Gao F,Ma Y,Xue T,Shen Y

Fri Nov 19 00:00:00 EST 2021

Loss of PRCD alters number and packaging density of rhodopsin in rod photoreceptor disc membranes.

Scientific reports

Sechrest ER,Murphy J,Senapati S,Goldberg AFX,Park PS,Kolandaivelu S

Wed Oct 21 00:00:00 EDT 2020

Leveraging Zebrafish to Study Retinal Degenerations.

Frontiers in cell and developmental biology

Angueyra JM,Kindt KS

Thu Oct 01 00:00:00 EDT 2020

Leveraging Zebrafish to Study Retinal Degenerations.

Frontiers in cell and developmental biology

Angueyra JM,Kindt KS

Thu Oct 01 00:00:00 EDT 2020

Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish.

The Journal of biological chemistry

Liu F,Qin Y,Yu S,Soares DC,Yang L,Weng J,Li C,Gao M,Lu Z,Hu X,Liu X,Jiang T,Liu JY,Shu X,Tang Z,Liu M

Fri Apr 14 00:00:00 EDT 2017

Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish.

The Journal of biological chemistry

Liu F,Qin Y,Yu S,Soares DC,Yang L,Weng J,Li C,Gao M,Lu Z,Hu X,Liu X,Jiang T,Liu JY,Shu X,Tang Z,Liu M

Fri Apr 14 00:00:00 EDT 2017

生物信息学

蛋白别名: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1; Guanine nucleotide-binding protein G(t) subunit alpha-1; guanine nucleotide-binding protein G(T), alpha-1 subunit; rod-type transducin alpha subunit; Tr alpha; Transducin alpha-1 chain; transducin, rod-specific

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基因别名: CSNB1G; CSNBAD3; GBT1; Gnat-1; GNAT1; GNATR; Ird1; Ird2; irdc; irdr; Tralpha; transducin

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UniProt ID: (Human) P11488, (Mouse) P20612

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Entrez Gene ID: (Human) 2779, (Mouse) 14685

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