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产品信息
PA5-120951
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 244-413 of human GOT1 (NP_002070.1).
偶联物
形式
Liquid
浓度
1.55 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914523
产品详细信息
Positive test controls include: HepG2, U-251MG, Mouse brain, Mouse liver, Mouse heart, Rat brain, Rat liver, Rat kidney. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: FVSEGFEFFC AQSFSKNFGL YNERVGNLTV VGKEPESILQ VLSQMEKIVR ITWSNPPAQG ARIVASTLSN PELFEEWTGN VKTMADRILT MRSELRARLE ALKTPGTWNH ITDQIGMFSF TGLNPKQVEY LVNEKHIYLL PSGRINVSGL TTKNLDYVAT SIHEAVTKIQ
靶标信息
GOT1 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aspartate aminotransferase 1; Aspartate aminotransferase, cytoplasmic; aspartate transaminase 1; cAspAT; cCAT; Cysteine aminotransferase, cytoplasmic; Cysteine transaminase, cytoplasmic; cytosolic aspartate aminotransferase; Glutamate oxaloacetate transaminase 1; glutamate oxaloacetate transaminase 1, soluble; glutamic-oxaloacetic transaminase 1, soluble; growth-inhibiting protein 18; testis secretory sperm-binding protein Li 196a; Transaminase A
基因别名: AI789014; Aspat; AST1; ASTQTL1; cAspAT; cCAT; Gaspat; GIG18; Got-1; GOT1
UniProt ID: (Human) P17174, (Rat) P13221, (Mouse) P05201
Entrez Gene ID: (Human) 2805, (Rat) 24401, (Mouse) 14718
L-aspartate:2-oxoglutarate aminotransferase activity
phosphatidylserine decarboxylase activity
pyridoxal phosphate binding
carboxylic acid binding
identical protein binding
L-cysteine:2-oxoglutarate aminotransferase activity
L-phenylalanine:2-oxoglutarate aminotransferase activity
catalytic activity
transaminase activity
transferase activity
transaminase
gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
glycerol biosynthetic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
Notch signaling pathway
cellular amino acid biosynthetic process
glutamate catabolic process to aspartate
glutamate catabolic process to 2-oxoglutarate
cellular response to insulin stimulus
response to glucocorticoid
fatty acid homeostasis
dicarboxylic acid metabolic process
cellular amino acid metabolic process
biosynthetic process
