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Proteintech

GPD1L Polyclonal Antibody

6 篇参考文献

查看其他6个GPD1L抗体

货号 17263-1-AP

此产品在中国无法购买

150 µL

抗体检测数据 (4)

Application

GPD1L Antibody in Western Blot (WB)

图: 1 / 4

GPD1L Antibody (17263-1-AP) in WB

Human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17263-1-AP (GPD1L antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

GPD1L Antibody in Western Blot (WB)

GPD1L Antibody in Western Blot (WB)

GPD1L Antibody in Western Blot (WB)

GPD1L Antibody in Western Blot (WB)

Product Image Gallery

GPD1L Antibody in Western Blot (WB) — Human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 17263-1-AP (GPD1L antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

GPD1L Antibody in Western Blot (WB) — Mouse heart tissue were subjected to SDS PAGE followed by western blot with 17263-1-AP (GPD1L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

GPD1L Antibody in Western Blot (WB) — Human brain tissue were subjected to SDS PAGE followed by western blot with 17263-1-AP (GPD1L antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

GPD1L Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 17263-1-AP (GPD1L antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

产品信息

17263-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

查看6篇已发表文章 6篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

GPD1L Fusion Protein Ag10977 (1-351 aa encoded by BC028726)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.13 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MAAAPLKVC IVGSGNWGSA VAKIIGNNVK KLQKFASTVK MWVFEETVNG RKLTDIINND HENVKYLPGH KLPENVVAMS NLSEAVQDAD LLVFVIPHQF IHRICDEITG RVPKKALGIT LIKGIDEGPE GLKLISDIIR EKMGIDISVL MGANIANEVA AEKFCETTIG SKVMENGLLF KELLQTPNFR ITVVDDADTV ELCGALKNIV AVGAGFCDGL RCGDNTKAAV IRLGLMEMIA FARIFCKGQV STATFLESCG VADLITTCYG GRNRRVAEAF ARTGKTIEEL EKEMLNGQKL QGPQTSAEVY RILKQKGLLD KFPLFTAVYQ ICYESRPVQE MLSCLQSHPE HT (1-351 aa encoded by BC028726)

靶标信息

The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis.

Molecular cell

Yao CH,Park JS,Kurmi K,Hu SH,Notarangelo G,Crowley J,Jacobson H,Hui S,Sharpe AH,Haigis MC

Thu Apr 20 00:00:00 UTC 2023

Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells.

Molecular cell

Wang Y,Stancliffe E,Fowle-Grider R,Wang R,Wang C,Schwaiger-Haber M,Shriver LP,Patti GJ

Thu Sep 01 00:00:00 UTC 2022

A ferroptosis defense mechanism mediated by glycerol-3-phosphate dehydrogenase 2 in mitochondria.

Proceedings of the National Academy of Sciences of the United States of America

Wu S,Mao C,Kondiparthi L,Poyurovsky MV,Olszewski K,Gan B

Tue Jun 28 00:00:00 UTC 2022

Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation.

Journal of translational medicine

Hao H,Yan S,Zhao X,Han X,Fang N,Zhang Y,Dai C,Li W,Yu H,Gao Y,Wang D,Gao Q,Duan Y,Yuan Y,Li Y

Mon Sep 05 00:00:00 UTC 2022

Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD⁺ to alleviate mitochondrial disease.

Cell metabolism

Liu S,Fu S,Wang G,Cao Y,Li L,Li X,Yang J,Li N,Shan Y,Cao Y,Ma Y,Dong M,Liu Q,Jiang H

Tue Oct 05 00:00:00 UTC 2021

A miR-210-3p regulon that controls the Warburg effect by modulating HIF-1α and p53 activity in triple-negative breast cancer.

Cell death & disease

Du Y,Wei N,Ma R,Jiang S,Song D

Wed Sep 09 00:00:00 UTC 2020

生物信息学

蛋白别名: Glycerol-3-phosphate dehydrogenase 1-like protein; GPD1-L

基因别名: 2210409H23Rik; D9Ertd660e; GPD1-L; GPD1L; KIAA0089; RGD1560123

UniProt ID: (Human) Q8N335, (Mouse) Q3ULJ0

Entrez Gene ID: (Human) 23171, (Mouse) 333433, (Rat) 363159

glycerol-3-phosphate dehydrogenase [NAD+] activity sodium channel regulator activity protein homodimerization activity ion channel binding NAD binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor molecular_function dehydrogenase

参与通路

regulation of heart rate carbohydrate metabolic process phosphatidic acid biosynthetic process NADH metabolic process positive regulation of sodium ion transport triglyceride biosynthetic process NAD metabolic process negative regulation of peptidyl-serine phosphorylation glycerol-3-phosphate catabolic process oxidation-reduction process regulation of ventricular cardiac muscle cell membrane depolarization ventricular cardiac muscle cell action potential negative regulation of protein kinase C signaling positive regulation of protein localization to cell surface regulation of sodium ion transmembrane transporter activity glycerol-3-phosphate metabolic process biological_process

1x1 image pixel for data collection