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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Gephyrin; gephyrin isoform; Putative glycine receptor-tubulin linker protein
基因别名: GEPH; GPH; GPHN; GPHRYN; HKPX1; KIAA1385; MOCODC
UniProt ID: (Human) Q9NQX3, (Rat) Q03555
Entrez Gene ID: (Human) 10243, (Rat) 64845