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GPNMB Antibody (MA5-50244) in Flow
Flow cytometry analysis overlay peak curve showing Hela cells stained with GPNMB monoclonal antibody (Product # MA5-50244) (red line) at 1x10^6 cells) for 45 min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1x10^6 cells) used under the same conditions. Acquisition of >10, 003 events was performed.
产品信息
MA5-50244
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3G2
抗原
Recombinant Human GPNMB protein
偶联物
形式
Liquid
浓度
0.83 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_3092484
靶标信息
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glycoprotein (transmembrane) nmb; glycoprotein nmb-like protein; glycoprotein nonmetastatic melanoma protein B; hematopoietic growth factor inducible neurokinin-1; Hematopoietic growth factor inducible neurokinin-1 type; osteoactivin; transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB
基因别名: GPNMB; HGFIN; NMB; UNQ1725/PRO9925
UniProt ID: (Human) Q14956
Entrez Gene ID: (Human) 10457
