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GPR125 Antibody (PA5-120377) in WB
Western blot analysis of GPR125 in extracts of Mouse liver. Samples were incubated with GPR125 Polyclonal antibody (Product # PA5-120377) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3 min.
产品信息
PA5-120377
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 370-600 of human ADGRA3 (NP_660333.2).
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2913949
产品详细信息
Positive test controls include: Mouse liver. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.
Immunogen sequence: ITAYLQCTRN THGSGIYPGN PQDERKAWRR CDRGGFWADD DYSRCQYAND VTRVLYMFNQ MPLNLTNAVA TARQLLAYTV EAANFSDKMD VIFVAEMIEK FGRFTKEEKS KELGDVMVDI ASNIMLADER VLWLAQREAK ACSRIVQCLQ RIATYRLAGG AHVYSTYSPN IALEAYVIKS TGFTGMTCTV FQKVAASDRT GLSDYGRRDP EGNLDKQLSF KCNVSNTFSS L
靶标信息
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adhesion G protein-coupled receptor A3; G protein-coupled receptor 125; G-protein coupled receptor 125; probable G-protein coupled receptor 125
基因别名: 3830613O22Rik; Adgra3; AU044632; Gpr125; Tem5-like
UniProt ID: (Mouse) Q7TT36
Entrez Gene ID: (Mouse) 70693, (Rat) 305408
