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GPR176 Antibody (PA3-046) in IHC (P)
Immunohistochemistry analysis of GPR176 was performed on blood vessels of human kidney tissue. To expose target proteins, antigen retrieval was performed by microwaving tissues for 20 minutes in 10mM sodium citrate buffer (pH 6.0). Tissue slides were probed with a GPR176 polyclonal antibody (Product # PA3-046) at a dilution of 1:3000, overnight at 4C in a humidified chamber. Tissues were washed, and detecti... View More
产品信息
PA3-046
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated COOH-terminal amino acids of 496-515 (RVERKMSRNNKVSIFPKVDS)
偶联物
Unconjugated
形式
Liquid
浓度
Conc. Not Determined
保存液
whole serum
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2663691
产品详细信息
GPR176 is in the G protein-coupled receptor family and are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bovine, Dog, Bat, Horse, Stickleback, Zebrafish (100%).
GPR176 exists in different glycosylated forms.
靶标信息
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR176 (G protein-coupled receptor 176), also known as HB-954, GPR or Gm1012, is a 515 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. Expressed in brain and spleen, with trace expression in kidney, GPR176 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell. Containing four N-glycosylation sites, seven transmembrane domains and a large C-terminal cytosolic domain, GPR176 is encoded by a gene mapping to human chromosome 15q14.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G-protein coupled receptor 176; G-protein coupled receptor AGR9; HB-954; HB954; probable G-protein coupled receptor 176
基因别名: Agr9; Gm1012; GPR176; HB-954
UniProt ID: (Human) Q14439, (Mouse) Q80WT4
Entrez Gene ID: (Human) 11245, (Mouse) 381413
