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产品信息
AGR-063-F-50UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide TLAKRFALKTRSQITKRKR, corresponding to amino residues 461-479 of rat CHRM3. Intracellular, 3rd loop.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: TLAKRFALKTRSQITKRKR^M
^M
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
GPR183 was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B lymphocytes. GPR183 is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EBI 2; EBI2; EBV-induced G-protein coupled receptor 2; EBV-induced G-protein coupled receptor 2 homolog; EBV-induced gene 2; Epstein-Barr virus induced gene 2; Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor); Epstein-Barr virus-induced G-protein coupled receptor 2; Epstein-Barr virus-induced G-protein coupled receptor 2 homolog; G-protein coupled receptor 183; RP11-461N23.2
基因别名: EBI2; GPR183
UniProt ID: (Human) P32249, (Rat) D4A7K7, (Mouse) Q3U6B2
Entrez Gene ID: (Human) 1880, (Rat) 679975, (Mouse) 321019
adaptive immune response
B cell activation involved in immune response
mature B cell differentiation involved in immune response
dendritic cell chemotaxis
immune response
humoral immune response
G-protein coupled receptor signaling pathway
T cell chemotaxis
osteoclast differentiation
leukocyte chemotaxis
positive regulation of B cell proliferation
dendritic cell homeostasis
T follicular helper cell differentiation
positive regulation of ERK1 and ERK2 cascade
regulation of astrocyte chemotaxis
biological_process
immune system process
signal transduction
