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产品信息
PA5-33718
产品规格
种属反应
Human,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 17 amino acid peptide from 3rd extracellular domain of human GPR43.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551091
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%).
靶标信息
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR43 is a member of this family (subfamily carboxylic acid). It expression has been reported primarily in immune cells including monocytes and neutrophils. An EST has been isolated from a human pancreatic library.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: fatty acid receptor 2; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein-coupled receptor 43; G-protein coupled receptor 43
基因别名: FFA2; FFA2R; FFAR2; GPCR43; GPR43
UniProt ID: (Human) O15552
Entrez Gene ID: (Human) 2867
leukocyte chemotaxis involved in inflammatory response
mucosal immune response
regulation of acute inflammatory response
positive regulation of cytokine production involved in immune response
cell surface pattern recognition receptor signaling pathway
positive regulation of acute inflammatory response to non-antigenic stimulus
G-protein coupled receptor signaling pathway
lipid storage
positive regulation of chemokine production
glucose homeostasis
fat cell differentiation
cellular response to fatty acid
regulation of peptide hormone secretion
positive regulation of interleukin-8 secretion
