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Immunogen sequence: MEAVAKFDF TASGEDELSF HTGDVLKILS NQEEWFKAEL GSQEGYVPKN FIDIQFPKWF HEGLSRHQAE NLLMGKEVGF FIIRASQSSP GDFSISVRHE DDVQHFKVMR DNKGNYFLWT EKFPSLNKLV DYYRTNSISR QKQIFLRDRT REDQGHRGNS LDRRSQGGPH LSGAVGEEIR PSMNRKLSDH PPTLPLQQHQ HQPQPPQYAP APQQLQQPPQ QRYLQHHHFH QERRGGSLDI NDGHCGTGLG SEMNAALMHR RHTDPVQLQA AGRVRWARAL YDFEALEDDE LGFHSGEVVE VLDSSNPSWW TGRLHNKLGL FPANYVAPMT R (1-330 aa encoded by BC026002)
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adapter protein GRID; GADS protein; GRB-2-like protein; GRB-2-related monocytic adapter protein; GRB2-related adapter protein 2; Grb2-related adaptor downstream of Sch; GRB2-related adaptor protein 2; GRB2-related protein with insert domain; GRB2L; GRBLG; GRBX; Grf-40; Grf40 adapter protein; Growth factor receptor-binding protein; growth factor receptor-bound protein 2-related adaptor protein 2; Hematopoietic cell-associated adapter protein GrpL; Hematopoietic cell-associated adaptor protein GrpL; MONA; monocytic adapter; monocytic adaptor; P38; Protein GADS; RP3-370M22.1; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule
基因别名: GADS; GRAP-2; GRAP2; GRB2L; GRBLG; GrbX; Grf40; GRID; GRPL; Mona; P38
UniProt ID: (Human) O75791, (Mouse) O89100
Entrez Gene ID: (Human) 9402, (Rat) 366962, (Mouse) 17444