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产品信息
TA500855
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2C11
抗原
Full length human recombinant protein of human GRIPAP1 produced in HEK293T cell.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GRASP-1; GRIP1; GRIP1-associated protein 1; MPMGp800B12492Q3
基因别名: GRASP-1; GRIPAP1; KIAA1167
UniProt ID: (Human) Q4V328
Entrez Gene ID: (Human) 56850
