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产品信息
PA5-45624
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human GSPT1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2609398
产品详细信息
Peptide sequence: AGGRAAPVES SQEEQSLCEG SNSAVSMELS EPIENGETEM SPEESWEHKE
Sequence homology: Cow: 93%; Dog: 87%; Human: 100%; Pig: 87%; Rabbit: 100%; Rat: 93%
靶标信息
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
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生物信息学
蛋白别名: Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; G1 to S phase transition protein 1 homolog
基因别名: 551G9.2; ERF3A; ETF3A; GSPT1; GST1
UniProt ID: (Human) P15170
Entrez Gene ID: (Human) 2935
