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Invitrogen
GSR Recombinant Rabbit Monoclonal Antibody (23GB2845)
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
图: 1 / 4
GSR Antibody (MA5-53478) in ICC/IF
Immunocytochemistry analysis of GSR in HeLa cells. Nuclei were stained blue with DAPI; GSR recombinant monoclonal antibody (Product # MA5-53478) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Very low. Scale bar: 20 μm.
产品信息
MA5-53478
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB2845
抗原
A synthesized peptide derived from human GLUR (470-522AA).
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122m; glutathione reductase; glutathione reductase 1; Glutathione reductase, mitochondrial; glutathione S-reductase; GR; GRase
基因别名: AI325518; D8Ertd238e; GLUR; Gr-1; Gr1; GRD1; GSR; HEL-75; HEL-S-122m
UniProt ID: (Human) P00390, (Mouse) P47791
Entrez Gene ID: (Human) 2936, (Mouse) 14782
glutathione-disulfide reductase activity
electron carrier activity
flavin adenine dinucleotide binding
NADP binding
oxidoreductase activity
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
protein homodimerization activity
glutathione binding
oxidoreductase
reductase
metabolite interconversion enzyme
