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产品信息
H00002969-M01
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3E2
抗原
GTF2I (AAH04472.1, 36 a.a. approximately 274 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: ELAKSKAEVA CIAVYETDVF VVGTERGRAF VNTRKDFQKD FVKYCVEEEE KAAEMHKMKS TTQANRMSVD AVEIETLRKT VEDYFCFCYG KALGKSTVVP VPYEKMLRDQ SAVVVQGLPE GVAFKHPENY DLATLKWILE NKAGISFIIK RPFLEPKKHV GGRVMVTDAD RSILSPGGSC GPIKVKTEPT EDSGISLEMA AVTVKEESED PDYYQYNIQG SHHSSEGNEG TEMEVPAEG
靶标信息
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11. 23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.
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生物信息学
蛋白别名: BAP-135; Bruton tyrosine kinase-associated protein 135; BTK-associated protein, 135kD; General transcription factor II-I; GTFII-I; OTTHUMP00000209509; SPIN; SRF-Phox1-interacting protein; tfiii; Williams-Beuren syndrome chromosomal region 6 protein; Williams-Beuren syndrome chromosome region 6
基因别名: BAP135; BTKAP1; DIWS; GTF2I; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6
UniProt ID: (Human) P78347
Entrez Gene ID: (Human) 2969
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
signal transduction
transition between slow and fast fiber
negative regulation of angiogenesis
negative regulation of cytosolic calcium ion concentration
