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GTPBP2 Antibody (PA5-75936) in WB
Western blot analysis of GTPBP2 in Lane 1: JURKAT whole cell lysate (56 µg), Lane 2: THP-1 whole cell lysate (42 µg), Lane 3: the Thymus whole cell lysate of rat (39 µg), Lane 4: the Testis tissue lysate of mouse (47 µg). Samples were incubated with GTPBP2 polyclonal antibody (Product # PA5-75936) at a dilution of 1:1,000.
产品信息
PA5-75936
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human GTPBP2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2719664
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP2 (GTP-binding protein 2) is a 602 amino acid G protein that is expressed in kidney, skeletal muscle, testis, brain and thymus, though it is not detected in liver. Expression of GTPBP2 is enhanced by ©-interferon stimulation in HeLa cells, THP-1 cells and thioglycollate-elicited mouse peritoneal macrophages. There are four isoforms of GTPBP2 that are expressed as a result of alternative splicing events. Since mutation of the gene encoding GTPBP1 does not lead to any phenotypic abnormalities, it is thought that there may be a genetic redundancy to make up for GTPBP1 lack-of-function. GTPBP2 shares 44% sequence similarity with GTPBP1 and also overlaps in expression pattern, suggesting that the GTPBP2 gene may compensate for GTPBP1 genetic abnormalities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GTP-binding protein 2; GTP-binding-like protein 2; GTPBP2
基因别名: GTPBP2; nmf205
UniProt ID: (Human) Q9BX10, (Mouse) Q3UJK4
Entrez Gene ID: (Human) 54676, (Mouse) 56055, (Rat) 363195
