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Galectin 9 Antibody (MA5-52081) in ICC/IF
Immunofluorescence analysis of Galectin 9 was performed using 70% confluent log phase THP-1 cells. The cells were fixed with 3% glyoxal for 2 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Galectin 9 Recombinant Rabbit Monoclonal Antibody (PSH02-45) at 0.1 µg/mL in 0.1% BSA, incubated at 4 degree celsius over... View More
产品信息
MA5-52081
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH02-45
抗原
Synthetic peptide within human LGALS9 aa 51-100.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3099399
产品详细信息
Tissue Specificity: Peripheral blood leukocytes and lymphatic tissues. Expressed in lung, liver, breast and kidney with higher levels in tumor endothelial cells than normal endothelium (at protein level).
Positive Control: THP-1 cell lysate, A549 cell lysate, rat liver tissue lysate.
Subcellular Location: Cytoplasm, Nucleus, Secreted.
Predicted band size: 40 kDa.
靶标信息
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 36 kDa beta-galactoside-binding lectin; Ecalectin; Gal-9; Gal9; Galectin-9; Galectin9; HOM HD 21; Lectin galactose binding soluble 9 (Galectin-9); Lectin, galactose binding, soluble 9 (Galectin-9); lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; Tumor antigen HOM-HD-21; UAT; Urate transporter/channel; urate transporter/channel protein
基因别名: HUAT; LGALS9; LGALS9A
UniProt ID: (Human) O00182, (Rat) P97840
Entrez Gene ID: (Human) 3965, (Rat) 25476
natural killer cell tolerance induction
chemotaxis
inflammatory response
female pregnancy
positive regulation of gene expression
negative regulation of gene expression
response to lipopolysaccharide
regulation of interleukin-4 production
regulation of interleukin-5 production
negative regulation of chemokine production
negative regulation of interferon-gamma production
negative regulation of tumor necrosis factor production
positive regulation of interleukin-4 production
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
toll-like receptor 2 signaling pathway
toll-like receptor 4 signaling pathway
p38MAPK cascade
positive regulation of NF-kappaB import into nucleus
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of mast cell degranulation
negative regulation of natural killer cell mediated cytotoxicity
negative regulation of activated T cell proliferation
positive regulation of viral entry into host cell
positive regulation of interleukin-1 beta secretion
positive regulation of NF-kappaB transcription factor activity
maternal process involved in female pregnancy
positive regulation of activated T cell autonomous cell death
ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
response to interleukin-1
cellular response to interferon-gamma
positive regulation of transforming growth factor beta production
positive regulation of monocyte chemotactic protein-1 production
mature conventional dendritic cell differentiation
cellular response to virus
regulation of p38MAPK cascade
positive regulation of interferon-gamma secretion
positive regulation of tumor necrosis factor secretion
positive regulation of interleukin-8 secretion
positive regulation of dendritic cell chemotaxis
negative regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of interleukin-13 secretion
positive regulation of dendritic cell apoptotic process
positive regulation of interleukin-6 secretion
positive regulation of interleukin-10 secretion
positive regulation of interleukin-12 secretion
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
positive regulation of dendritic cell differentiation
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
ion transport
signal transduction
