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Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in the gene encoding GATA4 have been associated with cardiac septal defects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DNA-binding protein GATA-GT2; GAT4; GATA-binding factor 4; GATA-binding protein 4; MGC126629; Transcription factor GATA-4
基因别名: ASD2; Gata-4; GATA4; TACHD; TOF; VSD1
UniProt ID: (Human) P43694, (Mouse) Q08369, (Rat) P46152
Entrez Gene ID: (Human) 2626, (Mouse) 14463, (Rat) 54254
分子生物学功能: DNA-binding transcription factor