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Specificity: ABS 050-45-02 binds human ghrelin and des-acyl ghrelin, and showed ~5% cross-Specificity with rat ghrelin in a sandwich ELISA using ABS 052-121 as biotinylated detection antibody.
Reactivity: ABS 050-45-02 binds human ghrelin in solution. ABS 050-45-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibody ABS 052-121-02.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AMCBX1; Appetite-regulating hormone; FIP-3; FIP3; Fip3p; ghrelin 27; ghrelin 28; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; Growth hormone secretagogue; Growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP; IP1; IP2; IPD2; Motilin-related peptide; NEMO; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; Protein M46
Gene Aliases: GHRL; MTLRP; UNQ524/PRO1066
UniProt ID: (Human) Q9UBU3
Entrez Gene ID: (Human) 51738
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