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产品信息
MA5-31744
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2B4H1
抗原
Purified recombinant fragment of human GRIK3 (AA: extra 32-173) expressed in E. coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787367
产品详细信息
MA5-31744 has been tested in indirect ELISA.
靶标信息
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); EAA5; Excitatory amino acid receptor 5; GluK3; GluR-7; glutamate receptor; Glutamate receptor 7; Glutamate receptor ionotropic, kainate 3; glutamate receptor, ionotropic, kainate 3
基因别名: EAA5; GLR7; GluK3; GLUR7; GluR7a; GRIK3
UniProt ID: (Human) Q13003
Entrez Gene ID: (Human) 2899
adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
G-protein coupled receptor binding
ionotropic glutamate receptor activity
extracellular-glutamate-gated ion channel activity
glutamate receptor activity
ligand-gated ion channel activity
kainate selective glutamate receptor activity
transmembrane signal receptor
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
ion transmembrane transport
ionotropic glutamate receptor signaling pathway
regulation of membrane potential
negative regulation of synaptic transmission, glutamatergic
