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This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GKRP; Glucokinase regulator; Glucokinase regulatory protein; hexokinase 4
基因别名: FGQTL5; GCKR; GKRP; GLRE
UniProt ID: (Human) Q14397, (Rat) Q07071, (Mouse) Q91X44
Entrez Gene ID: (Human) 2646, (Rat) 25658, (Mouse) 231103