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Proteintech

Glypican 1 Polyclonal Antibody

23 篇参考文献

查看其他10个Glypican 1抗体

说明书

实验方案

技术支持

货号 16700-1-AP

此产品在中国无法购买

150 µL

说明书

实验方案

技术支持

抗体检测数据 (4)

Application

Glypican 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 4

Glypican 1 Antibody (16700-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using 16700-1-AP (Glypican 1 antibody) at dilution of 1:100 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Glypican 1 Antibody in Western Blot (WB)

Glypican 1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

产品信息

16700-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看11篇已发表文章 11篇已发表文章

免疫组化 (IHC)

查看9篇已发表文章 9篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫细胞化学 (ICC/IF)

查看2篇已发表文章 2篇已发表文章

免疫沉淀 (IP)

0.5-4.0 µg

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Glypican 1 Fusion Protein Ag10095 (208-558 aa encoded by BC051279)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.33 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: ELRLRATRA FVAARSFVQG LGVASDVVRK VAQVPLGPEC SRAVMKLVYC AHCLGVPGAR PCPDYCRNVL KGCLANQADL DAEWRNLLDS MVLITDKFWG TSGVESVIGS VHTWLAEAIN ALQDNRDTLT AKVIQGCGNP KVNPQGPGPE EKRRRGKLAP RERPPSGTLE KLVSEAKAQL RDVQDFWISL PGTLCSEKMA LSTASDDRCW NGMARGRYLP EVMGDGLANQ INNPEVEVDI TKPDMTIRQQ IMQLKIMTNR LRSAYNGNDV DFQDASDDGS GSGSGDGCLD DLCGRKVSRK SSSSRTPLTH ALPGLSEQEG QKTSAASCPQ PPTFLLPLLL FLALTVARPR WR (208-558 aa encoded by BC051279)

靶标信息

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

GPC1 Is Associated with Poor Prognosis and Treg Infiltration in Colon Adenocarcinoma.

Computational and mathematical methods in medicine

Liu Y,Ren H,Yang MQ,Li JY

Wed Sep 28 00:00:00 UTC 2022

GPC1 promotes the growth and migration of colorectal cancer cells through regulating the TGF-β1/SMAD2 signaling pathway.

PloS one

Lu F,Chen S,Shi W,Su X,Wu H,Liu M

Thu Jun 09 00:00:00 UTC 2022

GPC1 promotes the growth and migration of colorectal cancer cells through regulating the TGF-β1/SMAD2 signaling pathway.

PloS one

Lu F,Chen S,Shi W,Su X,Wu H,Liu M

Thu Jun 09 00:00:00 UTC 2022

Glypican-1 is a novel immunohistochemical marker to differentiate poorly differentiated squamous cell carcinoma from solid predominant adenocarcinoma of the lung.

Translational lung cancer research

Kai Y,Amatya VJ,Kushitani K,Kambara T,Suzuki R,Fujii Y,Tsutani Y,Miyata Y,Okada M,Takeshima Y

Mon Feb 01 00:00:00 UTC 2021

Overexpression of Annexin A2 promotes proliferation by forming a Glypican 1/c-Myc positive feedback loop: prognostic significance in human glioma.

Cell death & disease

Li X,Nie S,Lv Z,Ma L,Song Y,Hu Z,Hu X,Liu Z,Zhou G,Dai Z,Song T,Liu J,Wang S

Fri Mar 12 00:00:00 UTC 2021

Overexpression of Annexin A2 promotes proliferation by forming a Glypican 1/c-Myc positive feedback loop: prognostic significance in human glioma.

Cell death & disease

Li X,Nie S,Lv Z,Ma L,Song Y,Hu Z,Hu X,Liu Z,Zhou G,Dai Z,Song T,Liu J,Wang S

Fri Mar 12 00:00:00 UTC 2021

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.

Nature communications

Le Thomas A,Ferri E,Marsters S,Harnoss JM,Lawrence DA,Zuazo-Gaztelu I,Modrusan Z,Chan S,Solon M,Chalouni C,Li W,Koeppen H,Rudolph J,Wang W,Wu TD,Walter P,Ashkenazi A

Wed Dec 15 00:00:00 UTC 2021

Heparan sulfate proteoglycan glypican-1 and PECAM-1 cooperate in shear-induced endothelial nitric oxide production.

Scientific reports

Bartosch AMW,Mathews R,Mahmoud MM,Cancel LM,Haq ZS,Tarbell JM

Mon May 31 00:00:00 UTC 2021

The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis.

Frontiers in cell and developmental biology

Colin-Pierre C,Berthélémy N,Belloy N,Danoux L,Bardey V,Rivet R,Mine S,Jeanmaire C,Maquart FX,Ramont L,Brézillon S

Tue Dec 28 00:00:00 UTC 2021

The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis.

Frontiers in cell and developmental biology

Colin-Pierre C,Berthélémy N,Belloy N,Danoux L,Bardey V,Rivet R,Mine S,Jeanmaire C,Maquart FX,Ramont L,Brézillon S

Tue Dec 28 00:00:00 UTC 2021

The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis.

Frontiers in cell and developmental biology

Colin-Pierre C,Berthélémy N,Belloy N,Danoux L,Bardey V,Rivet R,Mine S,Jeanmaire C,Maquart FX,Ramont L,Brézillon S

Tue Dec 28 00:00:00 UTC 2021

Hair Histology and Glycosaminoglycans Distribution Probed by Infrared Spectral Imaging: Focus on Heparan Sulfate Proteoglycan and Glypican-1 during Hair Growth Cycle.

Biomolecules

Colin-Pierre C,Untereiner V,Sockalingum GD,Berthélémy N,Danoux L,Bardey V,Mine S,Jeanmaire C,Ramont L,Brézillon S

Sat Jan 30 00:00:00 UTC 2021

Hair Histology and Glycosaminoglycans Distribution Probed by Infrared Spectral Imaging: Focus on Heparan Sulfate Proteoglycan and Glypican-1 during Hair Growth Cycle.

Biomolecules

Colin-Pierre C,Untereiner V,Sockalingum GD,Berthélémy N,Danoux L,Bardey V,Mine S,Jeanmaire C,Ramont L,Brézillon S

Sat Jan 30 00:00:00 UTC 2021

SALL4 is a useful marker for pediatric yolk sac tumors.

Pediatric surgery international

Wu P,Luo R,Sun B,Zhao J,Xu Q,Feng S,Chen X,Wang C

Mon Jun 01 00:00:00 UTC 2020

IGFBP6 regulates vascular smooth muscle cell proliferation and morphology via cyclin E-CDK2.

Journal of cellular physiology

Wang Z,Qi Y,Wang R,Wu W,Li Z,Wang M,Liu R,Zhang C,Li W,Wang S

Tue Dec 01 00:00:00 UTC 2020

miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse.

Matrix biology : journal of the International Society for Matrix Biology

Woods S,Barter MJ,Elliott HR,McGillivray CM,Birch MA,Clark IM,Young DA

Mon Apr 01 00:00:00 UTC 2019

The cancer cell glycocalyx proteoglycan Glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis.

Biorheology

Moran H,Cancel LM,Mayer MA,Qazi H,Munn LL,Tarbell JM

Thu Apr 23 00:00:00 UTC 2020

Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing.

Experimental gerontology

Perrot G,Colin-Pierre C,Ramont L,Proult I,Garbar C,Bardey V,Jeanmaire C,Mine S,Danoux L,Berthélémy N,Maquart FX,Wegrowski Y,Brézillon S

Tue Oct 15 00:00:00 UTC 2019

Decreased expression of GPC1 in human skin keratinocytes and epidermis during ageing.

Experimental gerontology

Perrot G,Colin-Pierre C,Ramont L,Proult I,Garbar C,Bardey V,Jeanmaire C,Mine S,Danoux L,Berthélémy N,Maquart FX,Wegrowski Y,Brézillon S

Tue Oct 15 00:00:00 UTC 2019

Glypican-1 immunohistochemistry does not separate mesothelioma from pulmonary adenocarcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Chiu K,Lee L,Cheung S,Churg AM

Sat Sep 01 00:00:00 UTC 2018

Glypican-1 immunohistochemistry does not separate mesothelioma from pulmonary adenocarcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Chiu K,Lee L,Cheung S,Churg AM

Sat Sep 01 00:00:00 UTC 2018

Glypican-1 immunohistochemistry is a novel marker to differentiate epithelioid mesothelioma from lung adenocarcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Amatya VJ,Kushitani K,Kai Y,Suzuki R,Miyata Y,Okada M,Takeshima Y

Tue May 01 00:00:00 UTC 2018

High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas.

World neurosurgery

Saito T,Sugiyama K,Hama S,Yamasaki F,Takayasu T,Nosaka R,Onishi S,Muragaki Y,Kawamata T,Kurisu K

Fri Sep 01 00:00:00 UTC 2017

High Expression of Glypican-1 Predicts Dissemination and Poor Prognosis in Glioblastomas.

World neurosurgery

Saito T,Sugiyama K,Hama S,Yamasaki F,Takayasu T,Nosaka R,Onishi S,Muragaki Y,Kawamata T,Kurisu K

Fri Sep 01 00:00:00 UTC 2017

Control of organization and function of muscle and tendon by thrombospondin-4.

Matrix biology : journal of the International Society for Matrix Biology

Frolova EG,Drazba J,Krukovets I,Kostenko V,Blech L,Harry C,Vasanji A,Drumm C,Sul P,Jenniskens GJ,Plow EF,Stenina-Adognravi O

Tue Jul 01 00:00:00 UTC 2014

Control of organization and function of muscle and tendon by thrombospondin-4.

Matrix biology : journal of the International Society for Matrix Biology

Frolova EG,Drazba J,Krukovets I,Kostenko V,Blech L,Harry C,Vasanji A,Drumm C,Sul P,Jenniskens GJ,Plow EF,Stenina-Adognravi O

Tue Jul 01 00:00:00 UTC 2014

生物信息学

蛋白别名: glypican proteoglycan 1; Glypican-1; GPI-anchored cell surface heparan sulfate proteoglycan; HSPG M12

基因别名: AI462976; glypican; GPC1; HSPG M12; HSPGM12

UniProt ID: (Human) P35052, (Mouse) Q9QZF2, (Rat) P35053

Entrez Gene ID: (Human) 2817, (Mouse) 14733, (Rat) 58920

功能

copper ion binding fibroblast growth factor binding laminin binding heparan sulfate proteoglycan binding collagen V binding protein binding

参与通路

Schwann cell differentiation heparan sulfate proteoglycan catabolic process myelin assembly negative regulation of fibroblast growth factor receptor signaling pathway retinoid metabolic process glycosaminoglycan biosynthetic process glycosaminoglycan catabolic process axon guidance glycosaminoglycan metabolic process positive regulation of skeletal muscle cell differentiation biological_process

Glypican 1 Polyclonal Antibody

Glypican 1 Antibody (16700-1-AP) in IHC (P)

产品信息

16700-1-AP

免疫印迹 (WB)

免疫组化 (IHC)

免疫组化（石蜡） (IHC (P))

免疫细胞化学 (ICC/IF)

免疫沉淀 (IP)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

产品详细信息

靶标信息

生物信息学

性能保障

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