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Invitrogen
Granzyme K Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Granzyme K Antibody (PA5-84586)
Relative expression in different tissues in IHC: Detection of differential expression levels of Granzyme K demonstrates antibody specificity. Immunohistochemical analysis of Granzyme K using anti-Granzyme K Polyclonal Antibody (Product #PA5-84586), shows significant staining of Granzyme K in tonsil and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of Granzyme K w... View More
产品信息
PA5-84586
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2791737
产品详细信息
Immunogen sequence: KCKVTGWGAT DPDSLRPSDT LREVTVTVLS RKLCNSQSYY NGDPFITKDM VCAGDAKGQK DS
靶标信息
Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Fragmentin-3; granzyme 3; Granzyme K; granzyme K (granzyme 3; tryptase II); granzyme K (serine protease, granzyme 3; tryptase II); Granzyme-3; GrK; NK-Tryp-2; NK-tryptase-2; tryptase II
基因别名: GZMK; TRYP2
UniProt ID: (Human) P49863
Entrez Gene ID: (Human) 3003
