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This target displays homology in the following species: Cow: 93%; Human: 100%; Mouse: 100%; Rat: 100%
RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594). Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre-mRNA splicing regulation (PubMed:19523114). Binds (via C-terminus) to poly(U) RNA (PubMed:19523114). Involved in mRNA translation regulation, probably at the initiation step (PubMed:21771594). Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: chromodomain helicase DNA binding protein 3 interacting protein; HABP4; Hyaluronan-binding protein 4; IHABP-4; intracellular antigen detected by monoclonal antibody Ki-1; Intracellular hyaluronan-binding protein 4; Ki-1/57 intracellular antigen
基因别名: HABP4; IHABP-4; IHABP4; Ki-1/57; SERBP1L
UniProt ID: (Human) Q5JVS0
Entrez Gene ID: (Human) 22927
分子生物学功能: RNA metabolism protein