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Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (86%), Xenopus laevis (89%), Bovine (98%).
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: eRF3 family member; ERF3-similar protein; ERFS; HBS1-like protein; HBS1-like translational GTPase; Hsp70 subfamily B suppressor 1-like protein
基因别名: EF-1a; eRF3c; ERFS; HBS1; HBS1L; HSPC276; KIAA1038
UniProt ID: (Human) Q9Y450
Entrez Gene ID: (Human) 10767
分子生物学功能:
translation factor