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Immunogen sequence: AERMTTREKK VLEAGMGKVT SASFGEESTP GQTNSETAVV ALTQDQPSEA ATGGATLAQT ISEAAIGGAM LGQTTSEEAV GGATPDQTTS EETVGGAILD QTTSEDAVGG ATLGQTTSEE AVGGATLAQT TSEAAMEGAT LDQTTSEEAP GGTELIQTPL ASSTDHQTPP TSPVQGTTPQ ISPSTLIGSL RTLELGSESQ GASESQAPGE ENLLGEAAGG QDMADSMLMQ GSRGLTDQAI FYAVTPLPWC PHLVAVCPIP AAGLDVTQPC GDCGTIQENW VCLSCYQVYC GRYINGHMLQ HHGNSGHPLV LSYIDLSAWC YYCQAYVHHQ ALLDVKNIAH QNKFGEDMPH PH
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ16239; HD6; HDA6; Histone deacetylase 6; Protein deacetylase HDAC6; protein phosphatase 1, regulatory subunit 90; Tubulin-lysine deacetylase HDAC6
基因别名: CPBHM; HD6; HDAC6; JM21; KIAA0901; PPP1R90
UniProt ID: (Human) Q9UBN7
Entrez Gene ID: (Human) 10013