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产品信息
IHC-00283
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 902 and 952 of human histone deacetylase 7A.
偶联物
形式
Liquid
浓度
0.10 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Horse, Guinea pig_10141, Orangutan, Monkey, Gorilla, Chimpanzee and Northern white-cheeked gibbon
靶标信息
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HD7; HD7a; hdac-7; Histone deacetylase 7; Histone deacetylase 7A; Protein deacetylase HDAC7
基因别名: 5830434K02Rik; HD7; HD7A; HDAC7; HDAC7A; mFLJ00062
UniProt ID: (Human) Q8WUI4, (Mouse) Q8C2B3
Entrez Gene ID: (Human) 51564, (Mouse) 56233
chromatin binding
transcription corepressor activity
protein kinase C binding
protein binding
SUMO transferase activity
protein kinase binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
activating transcription factor binding
metal ion binding
repressing transcription factor binding
14-3-3 protein binding
histone deacetylase activity
transcription factor binding
hydrolase activity
histone deacetylase activity (H3-K14 specific)
histone deacetylase activity (H3-K9 specific)
histone deacetylase activity (H4-K16 specific)
NAD-dependent histone deacetylase activity (H3-K9 specific)
NAD-dependent histone deacetylase activity (H4-K16 specific)
NAD-dependent histone deacetylase activity (H3-K18 specific)
histone modifying enzyme
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
transcription, DNA-templated
cell-cell junction assembly
chromatin modification
protein sumoylation
neuron differentiation
negative regulation of interleukin-2 production
negative regulation of osteoblast differentiation
neuron apoptotic process
histone H3 deacetylation
cellular response to mechanical stimulus
positive regulation of cell migration involved in sprouting angiogenesis
negative regulation of neuron death
negative regulation of NIK/NF-kappaB signaling
regulation of transcription, DNA-templated
inflammatory response
nervous system development
histone deacetylation
B cell differentiation
B cell activation
negative regulation of striated muscle tissue development
negative regulation of transcription, DNA-templated
