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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEGMDKETFE FKFGKELTFT TVLSDQQVVE LIPGGAGIVV GYGDRSRFIQ LVQKARLEES KEQVAAMQAG LLKVVPQAVL DLLTWQELEK KVCGDPEVTV DALRKLTRFE DFEPSDSRVQ YFWEALNNFT NEDRSRFLRF VTGRSRLPAR IYIYPDKLGY ETTDALPESS TCSSTLFLPH YASAKVCEEK LRYAAYNCVA IDTDMSPWEE
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase HECTD3; HECT domain containing E3 ubiquitin protein ligase 3; HECT domain-containing protein 3; HECT-type E3 ubiquitin transferase HECTD3
基因别名: HECTD3
UniProt ID: (Human) Q5T447
Entrez Gene ID: (Human) 79654
分子生物学功能: ubiquitin-protein ligase