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产品信息
H00204851-M07
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
4E1
抗原
HIPK1 (AAH28408, 330 a.a. approximately 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: CTPLMVATLH PQVATITPQY AVPFTLSCAA GRPALVEQTA AVLQAWPGGT QQILLPSTWQ QLPGVALHNS VQPTAMIPEA MGSGQQLADW RNAHSHGNQY S
靶标信息
HIPK1 phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. The protein encoded by HIPK1 belongs to the Ser/Thr family of protein kinases and HIPK subfamily. Alternative splicing results in four transcript variants encoding four distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeodomain interacting protein kinase 1-like protein; Homeodomain-interacting protein kinase 1; nuclear body associated kinase 2b; Nuclear body-associated kinase 2
基因别名: HIPK1; KIAA0630; MYAK; NBAK2
UniProt ID: (Human) Q86Z02
Entrez Gene ID: (Human) 204851
eye development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
smoothened signaling pathway
positive regulation of cell proliferation
anterior/posterior pattern specification
regulation of tumor necrosis factor-mediated signaling pathway
retina layer formation
neuron differentiation
adherens junction assembly
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of angiogenesis
embryonic camera-type eye morphogenesis
embryonic retina morphogenesis in camera-type eye
definitive hemopoiesis
lens induction in camera-type eye
iris morphogenesis
endothelial cell apoptotic process
extrinsic apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
