Invitrogen

HIPK2 Polyclonal Antibody

查看其他14个HIPK2抗体

抗体检测数据 (8)

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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HIPK2 Antibody (PA5-40567) in IHC (P)

Immunohistochemistry (paraffin-embedded) analysis of human adult heart tissue using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HIPK2 Antibody in Western Blot (WB)

HIPK2 Antibody in Western Blot (WB)

HIPK2 Antibody in Western Blot (WB)

Product Image Gallery

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (paraffin-embedded) analysis of human adult heart tissue using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (paraffin-embedded) analysis of human cardiac tissue using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (paraffin-embedded) analysis of human neural tissue using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (paraffin-embedded) analysis of human pineal tissue using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

HIPK2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (paraffin-embedded) analysis of human heart tissue using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

HIPK2 Antibody in Western Blot (WB) — Western blot analysis of HepG2 cell lysate using an anti-HIPK2 polyclonal antibody (Product # PA5-40567). Lane 1) Primary Antibody; Lane 2) Primary Antibody + Blocking Peptide.

HIPK2 Antibody in Western Blot (WB) — Western blot analysis of human Jurkat cell lysate using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

HIPK2 Antibody in Western Blot (WB) — Western blot analysis of human HepG2 cell lysate using an anti-HIPK2 polyclonal antibody (Product # PA5-40567).

产品信息

PA5-40567

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1-1 µg/mL

-

免疫组化（石蜡） (IHC (P))

1:100-1:500

-

免疫细胞化学 (ICC/IF)

-

- -

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human HIPK2

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2605444

产品详细信息

Peptide sequence: MWSLGCVIAE LFLGWPLYPG ASEYDQIRYI SQTQGLPAEY LLSAGTKTTR

Sequence homology: Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 87%

靶标信息

HIPK2 is a nuclear serine/threonine kinase that is linked to transcriptional regulation and apoptosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: hHIPk2; Homeodomain-interacting protein kinase 2; Nuclear body-associated kinase 1; Sialophorin tail-associated nuclear serine/threonine-protein kinase

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基因别名: 1110014O20Rik; B230339E18Rik; HIPK2; Nbak1; PRO0593; Stank

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UniProt ID: (Human) Q9H2X6, (Mouse) Q9QZR5

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Entrez Gene ID: (Human) 28996, (Mouse) 15258

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RNA polymerase II activating transcription factor binding RNA polymerase II transcription coactivator activity transcription corepressor activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding SMAD binding virion binding nucleotide binding DNA binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups

参与通路

negative regulation of transcription from RNA polymerase II promoter eye development transcription, DNA-templated protein phosphorylation DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator transforming growth factor beta receptor signaling pathway smoothened signaling pathway adult walking behavior positive regulation of cell proliferation anterior/posterior pattern specification retina layer formation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation modulation by virus of host morphology or physiology neuron differentiation erythrocyte differentiation positive regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway PML body organization positive regulation of protein binding intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of DNA binding negative regulation of neuron apoptotic process positive regulation of angiogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade embryonic camera-type eye morphogenesis voluntary musculoskeletal movement positive regulation of sequence-specific DNA binding transcription factor activity regulation of cell cycle embryonic retina morphogenesis in camera-type eye lens induction in camera-type eye SMAD protein signal transduction iris morphogenesis cellular response to hypoxia intrinsic apoptotic signaling pathway regulation of signal transduction by p53 class mediator positive regulation of protein phosphorylation regulation of transcription, DNA-templated apoptotic process cellular response to DNA damage stimulus adult locomotory behavior phosphorylation negative regulation of nucleic acid-templated transcription