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产品信息
MA1-71500
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3F2
抗原
Recombinant Nef protein of HIV-1 HXB2 purified from E. coli
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
0.1% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_962108
产品详细信息
This antibody reacts with HIV-1 subtype C Nef of BRU, IIIB, LAV and HAN strains. It has been mapped to amino acids 31-35 (-GAASR-, HIV-1 HXB2).
靶标信息
HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells. The name derives from its negative factor thought at the beginning but presently it is remarked as the protein which bears a most distinctive biological characteristic of AIDS virus. The protein interacts directly with the signal transduction protein of the host T cell and works effectively on AIDS infection or on long term survival of the infected cells or induces apoptosis of non-infected cells. It is also involved in the endocytosis and degradation of receptor protein of the cell surface such as CD 4 and MH4, important for AIDS virus infection.
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生物信息学
蛋白别名: HIV-1 Nef
