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MA5-17015 recognizes HIV-2 Nef and does not cross react with HIV-1 Nef.
MA5-17015 has been successfully used in immunoprecipitation and Western blot applications.
The MA5-17015 immunogen is a TrpE-Fusion protein produced in X63Ag8.653 cells.
Nef is a multifunctional protein of 27 kDa in HIV-1 and 35 kDa in HIV-2. It induces the endocytosis of CD4 Receptor and reduces the MHC-1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HIV-2; HIV-2 nef; HIV2 nef protein; Nefprotein